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#COVID19

104 posts86 participants11 posts today

#FYI #US #USA #disease #diseases #AMA #AmericanMedicalAssociation #AkikoIwasaki #ToddUnger #covid19 #sarscov2 #covid #longcovid

"What is long COVID? What are the signs of long COVID? Does getting COVID multiple times increase long COVID risk? What long COVID treatments are available?"

"Akiko Iwasaki, PhD, Sterling Professor of Immunobiology at Yale University, discusses new long COVID research."

youtube.com/watch?v=ilIOh4cZiNI

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🧵
Tähän ketjuun.

”Alustava tutkimushanke, jossa etsitään hoitoa #LongCovid’in oireisiin, on käynnissä, kun pandemian alkamisesta on kulunut 5 vuotta”

”Puhuessaan kokemuksistaan kokeiluissa 3 viikkoa lääkityksen saamisen jälkeen Ryan sanoi, että se tuntui siltä kuin se olisi antanut hänelle elämän takaisin”
”Hän sanoi: ”Tuntuu kuin olisin saanut uudet keuhkot. Hengitykseni tuntuu paremmalta ja pystyn tekemään enemmän ilman, että lepään niin paljon””

This week's Featured Links post has links to articles about how Starliner’s flight to the space station was far wilder than most of us thought, a growing conservation burial movement, the sprawling 'metroburb' where 'Severance' is filmed, and nine more.

coredump3.blogspot.com/2025/04

#AI, #COVID19, #Environment, #Finance, #Medical, #Movies #TV, #Politics, #Programming, #Science, #Security, #Society, #Space, #Technology

coredump3.blogspot.comFeatured Links - April 7, 2025Links to things I found interesting but didn't want to do a full blog post about. A floor-cleaning robot   Starliner’s flight to the space s...
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🧵
Vastaus Suzanne O’Sullivanille

#LongCovid on yhtä biolääketieteellinen kuin murtunut jalka.Väite, että se on #psykosomaattinen, ei ainoastaan jätä huomiotta tätä tiedettä, vaan se vahvistaa haitallista leimautumista, viivästyttää diagnoosia ja heikentää toipumista.Emme vastusta vivahteikasta keskustelua mielen ja kehon välisestä yhteydestä, mutta kun tiedotusvälineet antavat happea todistamattomille mielipiteille ilman tasapainoa, siitä on vaarana olla todellista haittaa”

medRxiv · Dysautonomia in long COVID is prevalent and could explain the frequency of symptomsBackground Long COVID presents with a variety of symptoms. Some of those symptoms could be related to autonomic dysfunction. Our aim is to evaluate the prevalence of autonomic dysfunction in long COVID patients. Methods We conducted a cross-sectional study and included all consecutive patients enrolled in several clinical research studies. We performed the following autonomic dysfunction markers: heart rate variability, heart rate, systolic and diastolic blood pressure changes during NASA lean test, cardiopulmonary exercise testing and a COMPASS-31 scale. We used linear regression to calculate the contribution of each dysautonomia measure on symptom burden as measured by the modified COVID-19 Yorkshire scale. Results We included 100 patients for this study. Our sample had a mean age of 56+/-11 years, included 53% minorities and 32% were women. Dysautonomia as defined by an abnormal COMPASS-31 was seen in 82%; 95% 72-89 while cardiovascular resting dysautonomia as represented by an abnormal heart rate variability was seen in 60%; 95% 48-70 of the population, orthostatic hypotension in 12% and POTS in 10%. In our adjusted analysis, we found that the beta coefficient for the COMPASS-31 score (0.37) was significant on changes in a self-reported long COVID symptom burden. The orthostatic intolerance and gastrointestinal domains of the COMPASS-31 was associated the highest long COVID symptom burden. Conclusion Dysautonomia is common in long COVID patients and contributes to the overall symptoms seen in long COVID. Identifying dysautonomia has important diagnostic and therapeutic implications. ### Competing Interest Statement The authors have declared no competing interest. ### Clinical Trial NA ### Funding Statement Yes ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: All studies were approved by the research ethics committees at the Miami VAHS and NOVA Southeastern University and all participants signed informed consent prior to participation. Miami VA is the IRB of record I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable. Yes Data cannot be shared publicly because it is owned but the Veterans Affairs.

Sarah's Tasmanian 'career change' sounds like a dream — until you hear her full story
By Hayley Gleeson

What about the people who change their career not to scratch some creative or philanthropic itch or make a truckload of money, but out of necessity — because illness or injury derailed or destroyed their ability to work?

abc.net.au/news/2025-04-07/car

ABC News · When illness forced Sarah out of work, she thought she'd be off for six months. It turned into eight yearsBy Hayley Gleeson

#Followerpower Im Rahmen einer Gesprächsrunde zur Aufarbeitung der #CoronaKrise wurde die folgende These formuliert. Wenn ihr in der Lage seid, diese sachlich fundiert zu veri- oder falsifizieren, bitte um Kommentar oder (wenn längerer Text) gerne auch einen Link mit kurzem Kommentar, warum ihr diesen Link für geeignet haltet. Falls du dich in einem fachlich kompetenten Umfeld bewegst, bin ich dich für's Weiterleiten /#boost auch sehr dankbar :mastolove:

> These: Die im Verlauf der Pandemie aufgetretenen Krisen im Gesundheitssystem, insbesondere der Personalmangel in den Krankenhäusern, wurden auch dadurch verursacht, dass Mitarbeiter nur aufgrund eines positiven PCR-Tests nicht weiter an der Behandlung und Pflege von Krankenhauspatienten mitwirken konnten. Richtig wäre gewesen, sie erst beim Auftreten von Symptomen vom direkten Kontakt mit Patienten abzuziehen. (Ende der These)

It's time to start digging in to my mask project!

I need good, solid resources to back up a presentation I'll be giving to the local public. What are the most reliable and ethical doctors, journalists, advocates, research, statistics, or sites that you've seen?

I'll be talking about air quality, advocating environmental justice through citizen science and mutual aid, and my focus is going to be ventilation and masking.

The program is organized by a local group of folks that started putting up air sensors all over town because of toxic chemical leaks from nearby refineries. They got a grant through a university, and they may be able to help me out in getting an air quality sensor so I can test the CO2 in local buildings. I'd also like to be able to pass out some mask samples. I've been trying to find info on other things like sip valves, elastomeric respirator exhaust valve filter adapters, good sites to buy masks and so on.

Since these issues got politicized and the CDC and WHO are increasingly corrupt/hamstrung, finding good info is a fuckin MESS. I could really use some help!

What's been very interesting to me is, the folks who promote masking are usually ALSO right on other issues. Masks are required at the local anarchist book fairs, for example, which to me says a LOT. The people I follow here on Mastodon who are solidly against genocide, fascism, capitalism, and lesser evilism are the SAME people who are solidly for issues like universal healthcare, right to repair, accessibility, direct action, labor organizing, etc etc-- you have a moral consistency that inspires my respect and hope, and I want to learn more from you!

Next post below will be where I list the sources I've collected, updating as I go.

#masks
#respirators
#ventilation
#COVID19
#covidCautious
#birdFlu
#H5N1
#measles
#publicHealth
#airQuality
#environmentalJustice
#mutualAid
#purpleAir
#citizenScience

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Fun facts about my spreadsheet of #COVID19 studies: If you simply read down the column of brief quotes captured from each study:

- It'd take you eight hours to get through the summaries, and
- You'll never take another COVID infection as lightly as you do today.

My spreadsheet of #COVID19 studies finding longer-term risks from infections has grown to 1,900 studies. Recent studies find:

- Increasing Long COVID risks with reinfection in kids
- Higher rates of bacterial, fungal, and viral infections for 12 months after COVID
- Vascular function may not improve within 1.5 years after COVID-19
- Brain alterations in children following mild COVID-19
- COVID-19 is associated with poor sperm quality

docs.google.com/spreadsheets/d

Google DocsCOVID-19/SARS-CoV-2 Studies

STUDY finds that Long #COVID19 patients at a rehabilitation clinic showed a lower quality of life than patients with asthma or COPD, accompanied by poor mental health. Association of SSD (somatic symptom disorder) with DLI (daily life impairment) was stronger in PCS than in asthma, and was not significant in COPD.

nature.com/articles/s41598-025

NatureThe implications of somatic symptom disorder on the impairment of daily life are greater in post-COVID syndrome than in asthma or COPD - results of a cross-sectional study in a rehabilitation clinic - Scientific ReportsThe aim was to compare the relationship between somatic symptom disorder (SSD), anxiety, depression, clinical symptoms, and daily life impairment (DLI) in post-COVID syndrome (PCS), asthma and chronic obstructive pulmonary disease (COPD). In a cross-sectional study, 371 patients (161 PCS, 121 asthma, 89 COPD) of a pulmonary rehabilitation clinic received the questionnaires PHQ-15 (Patient Health Questionnaire-15) and SSD-12 (Somatic Symptom Disorder-12) to determine SSD, GAD-7 (Generalized Anxiety Disorder-7) to determine anxiety disorder, and PHQ-9 (Patient Health Questionnaire-9) to determine depression. Lung function was estimated using whole-body plethysmography. Predictors for DLI were assessed by regression models and ROC analyses. Association of SSD with DLI was stronger in PCS (odds ratio 13.8; 95% confidence interval 1.7-109.9) than in asthma (8.5; 2.4–30.1), and was not significant in COPD (1.9; 0.5–7.5). In asthma and COPD, strongest predictors were GAD-7 (15.0; 1.9-116.8) and PHQ-9 (8.9; 1.1–71.8), respectively. Diffusion capacity was predictive in COPD (0.947; 0.916–0.979) and asthma (0.967; 0.943–0.993), but not in PCS. To conclude, SSD appears to have greater impact on DLI in PCS than asthma or COPD patients. This should be recognized appropriately during rehabilitation. Furthermore, increased psychological comorbidity should also be considered and adequately treated in asthma and COPD if necessary.