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#strains

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#Identification of #Dual #Receptor-binding Specific #Strains of #Human #H5N1 Viruses in #China, Biomed Envr Sci. (2012): sciencedirect.com/science/arti

Dual binding preference to 2, 3 and 2, 6-glycans were found in two strains: A/Guangdong/1/06 (A/GD/1/06) and A/Guangxi/1/08 (A/GX/1/08). Though minor effect of short-2, 6-binding was detected in A/GX/1/08 at a low virus titer, both showed high affinity to the oligosaccharide at a high load.

Emergence of a triple #reassortment avian #influenza virus (A/ #H5N6) from wild #birds, J Infect. doi.org/10.1016/j.jinf.2024.01

-- the isolate was located in Clade 2.3.4.4b1, which is in Clade 2.3.4.4b with the #strains currently prevalent in #poultry hosts on the live bird #market and the #vaccine strains currently found in China (Re-14 and rHN5801). SZ1 belongs to the same branch as the H5N6 strain originating from farm #dogs reported by Yao et al. in GISAID in 2023.

Continued thread

''In 2022, flu #H3N2 viruses predominated over #H1N1pdm09 & B viruses, accounting for 77% of all viruses analysed. Majority of #H1N1pdm09, #H3N2 & flu B viruses analysed at Centre were found to be antigenically and genetically similar to respective #WHO recommended #vaccine #strains for the S hemisphere in 2022. Of 3,372 samples tested for susceptibility to the #NAIs #oseltamivir & #zanamivir, 2 H1N1pdm09 viruses showed highly reduced inhibition against oseltamivir.''